Distribution, transport, and degradation of apolipoprotein B-100 in HepG2 cells

Distribution, transport, and degradation of apolipoprotein B-100 in HepG2 cells

The transport of apolipoprotein B (apoB) between the endoplasmic reticulum (ER) and Golgi was studied in puromycin-synchronized HepG2 cells, using an antibody that could distinguish between apoB in ER and Golgi compartments. In cells with normal ER-to-Golgi transport, both albumin and apoB colocaliz...

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Bibliographic Details
Main Authors: Nobuhiro Sakata, Thomas E. Phillips, Joseph L. Dixon
Format: Article
Language:English
Published: Elsevier 2001-12-01
Series:Journal of Lipid Research
Subjects:
albumin
endoplasmic reticulum
Golgi
microsomal triglyceride transfer protein
proteasome
protein degradation
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520315236

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http://www.sciencedirect.com/science/article/pii/S0022227520315236

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