BST2 regulates interferon gamma-dependent decrease in invasion of HTR-8/SVneo cells via STAT1 and AKT signaling pathways and expression of E-cadherin

BST2 regulates interferon gamma-dependent decrease in invasion of HTR-8/SVneo cells via STAT1 and AKT signaling pathways and expression of E-cadherin

The mechanism by which interferon-gamma (IFN-γ) downregulates trophoblast invasion needs further investigation. Treatment of HTR-8/SVneo cells with IFN-γ led to a decrease in their invasion concomitant with an increased expression of BST2. Silencing of BST2 by siRNA showed a significant increase in...

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Bibliographic Details
Main Authors: Sonam Verma, Amandeep Kaur Kang, Rahul Pal, Satish Kumar Gupta
Format: Article
Language:English
Published: Taylor & Francis Group 2020-01-01
Series:Cell Adhesion & Migration
Subjects:
ifn-γ
bst2
trophoblast invasion
e-cadherin
stat1
akt
Online Access:http://dx.doi.org/10.1080/19336918.2019.1710024

Internet

http://dx.doi.org/10.1080/19336918.2019.1710024

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