The Combination of Computational and Biosensing Technologies for Selecting Aptamer against Prostate Specific Antigen

Herein, we report a method of combining bioinformatics and biosensing technologies to select aptamers against prostate specific antigen (PSA). The main objective of this study is to select DNA aptamers with higher binding affinity for PSA by using the proposed method. Based on the five known sequenc...

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Bibliographic Details
Main Authors: Pi-Chou Hsieh, Hui-Ting Lin, Wen-Yih Chen, Jeffrey J. P. Tsai, Wen-Pin Hu
Format: Article
Language:English
Published: Hindawi Limited 2017-01-01
Series:BioMed Research International
Online Access:http://dx.doi.org/10.1155/2017/5041683