Increasing fidelity and efficiency by modifying cytidine base-editing systems in rice

Increasing fidelity and efficiency by modifying cytidine base-editing systems in rice

The efficiency of plant cytidine base-editing systems is limited, and unwanted mutations frequently occur in transgenic plants. We increased the cytidine editing frequency and fidelity of the plant base editor 3 (BE3) and targeted activation-induced cytidine deaminase (CDA) (target-AID) systems by c...

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Bibliographic Details
Main Authors: Ruiying Qin, Shengxiang Liao, Juan Li, Hao Li, Xiaoshuang Liu, Jianbo Yang, Pengcheng Wei
Format: Article
Language:English
Published: KeAi Communications Co., Ltd. 2020-06-01
Series:Crop Journal
Subjects:
CRISPR-Cas9
Base editing
BE3
CDA
Oryza sativa
Online Access:http://www.sciencedirect.com/science/article/pii/S2214514119300716

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http://www.sciencedirect.com/science/article/pii/S2214514119300716

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