Efficient support of virus-like particle assembly by the HIV-1 packaging signal

The principal structural component of a retrovirus particle is the Gag protein. Retroviral genomic RNAs contain a ‘packaging signal’ (‘Ψ') and are packaged in virus particles with very high selectivity. However, if no genomic RNA is present, Gag assembles into particles containing cellular mRNA...

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Bibliographic Details
Main Authors: Mauricio Comas-Garcia, Tomas Kroupa, Siddhartha AK Datta, Demetria P Harvin, Wei-Shau Hu, Alan Rein
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2018-08-01
Series:eLife
Subjects:
HIV
RNA
Online Access:https://elifesciences.org/articles/38438