IL-17F depletion accelerates chitosan conduit guided peripheral nerve regeneration

IL-17F depletion accelerates chitosan conduit guided peripheral nerve regeneration

Abstract Peripheral nerve injury is a serious health problem and repairing long nerve deficits remains a clinical challenge nowadays. Nerve guidance conduit (NGC) serves as the most promising alternative therapy strategy to autografts but its repairing efficiency needs improvement. In this study, we...

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Bibliographic Details
Main Authors: Feixiang Chen, Weihuang Liu, Qiang Zhang, Ping Wu, Ao Xiao, Yanan Zhao, Ying Zhou, Qiaona Wang, Yun Chen, Zan Tong
Format: Article
Language:English
Published: BMC 2021-07-01
Series:Acta Neuropathologica Communications
Subjects:
IL-17F
Macrophage polarization
Peripheral nerve regeneration
Nerve guidance conduit
Immune microenvironment
Online Access:https://doi.org/10.1186/s40478-021-01227-1

Internet

https://doi.org/10.1186/s40478-021-01227-1

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