Epigenetic landscapes suggest that genetic risk for intracranial aneurysm operates on the endothelium

Epigenetic landscapes suggest that genetic risk for intracranial aneurysm operates on the endothelium

Abstract Background Genetics play an important role in intracranial aneurysm (IA) pathophysiology. Genome-wide association studies have identified several single nucleotide polymorphisms (SNPs) that are linked to IA but how they affect disease pathobiology remains poorly understood. We used Encyclop...

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Bibliographic Details
Main Authors: Kerry E. Poppenberg, Kaiyu Jiang, Michael K. Tso, Kenneth V. Snyder, Adnan H. Siddiqui, John Kolega, James N. Jarvis, Hui Meng, Vincent M. Tutino
Format: Article
Language:English
Published: BMC 2019-10-01
Series:BMC Medical Genomics
Subjects:
Cell type
Cerebral aneurysm
Epigenetics
Genetics
Risk
Online Access:http://link.springer.com/article/10.1186/s12920-019-0591-7

Internet

http://link.springer.com/article/10.1186/s12920-019-0591-7

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