Cell biology and genetics of minimal change disease [version 1; referees: 2 approved]

Minimal change disease (MCD) is an important cause of nephrotic syndrome and is characterized by massive proteinuria and hypoalbuminemia, resulting in edema and hypercholesterolemia. The podocyte plays a key role in filtration and its disruption results in a dramatic loss of function leading to prot...

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Bibliographic Details
Main Authors: Moin A. Saleem, Yasuko Kobayashi
Format: Article
Language:English
Published: F1000 Research Ltd 2016-03-01
Series:F1000Research
Subjects:
Online Access:http://f1000research.com/articles/5-412/v1