Cell biology and genetics of minimal change disease [version 1; referees: 2 approved]
Minimal change disease (MCD) is an important cause of nephrotic syndrome and is characterized by massive proteinuria and hypoalbuminemia, resulting in edema and hypercholesterolemia. The podocyte plays a key role in filtration and its disruption results in a dramatic loss of function leading to prot...
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
F1000 Research Ltd
2016-03-01
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Series: | F1000Research |
Subjects: | |
Online Access: | http://f1000research.com/articles/5-412/v1 |