Rapid MALDI-MS Assays for Drug Quantification in Biological Matrices: Lessons Learned, New Developments, and Future Perspectives

Rapid MALDI-MS Assays for Drug Quantification in Biological Matrices: Lessons Learned, New Developments, and Future Perspectives

Matrix-assisted laser desorption/ionization mass spectrometry (MALDI-MS) has rarely been used in the field of therapeutic drug monitoring, partly because of the complexity of the ionization processes between the compounds to be quantified and the many MALDI matrices available. The development of a v...

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Bibliographic Details
Main Authors: Margaux Fresnais, Esra Yildirim, Seda Karabulut, Dirk Jäger, Inka Zörnig, Julia Benzel, Kristian W. Pajtler, Stefan M. Pfister, Jürgen Burhenne, Walter E. Haefeli, Rémi Longuespée
Format: Article
Language:English
Published: MDPI AG 2021-02-01
Series:Molecules
Subjects:
mass spectrometry
MALDI
therapeutic drug monitoring
targeted quantification
Online Access:https://www.mdpi.com/1420-3049/26/5/1281

Internet

https://www.mdpi.com/1420-3049/26/5/1281

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