Brain-Site-Specific Proteome Changes Induced by Neuronal P60TRP Expression

p60 transcription regulator protein (p60TRP) facilitates the processing of the amyloid precursor protein towards the non-amyloidogenic pathway by inhibiting the β-secretase action. This protein was initially identified to be downregulated in the temporal lobe of brains from Alzheimer's disease...

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Bibliographic Details
Main Authors: Arulmani Manavalan, Manisha Mishra, Siu Kwan Sze, Klaus Heese
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2013-02-01
Series:Neurosignals
Subjects:
Online Access:http://www.karger.com/Article/FullText/343672