Brain-Site-Specific Proteome Changes Induced by Neuronal P60TRP Expression
p60 transcription regulator protein (p60TRP) facilitates the processing of the amyloid precursor protein towards the non-amyloidogenic pathway by inhibiting the β-secretase action. This protein was initially identified to be downregulated in the temporal lobe of brains from Alzheimer's disease...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
Cell Physiol Biochem Press GmbH & Co KG
2013-02-01
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Series: | Neurosignals |
Subjects: | |
Online Access: | http://www.karger.com/Article/FullText/343672 |