Evaluating cellular polyfunctionality with a novel polyfunctionality index.

Functional evaluation of naturally occurring or vaccination-induced T cell responses in mice, men and monkeys has in recent years advanced from single-parameter (e.g. IFN-γ-secretion) to much more complex multidimensional measurements. Co-secretion of multiple functional molecules (such as cytokines...

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Bibliographic Details
Main Authors: Martin Larsen, Delphine Sauce, Laurent Arnaud, Solène Fastenackels, Victor Appay, Guy Gorochov
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3408490?pdf=render