BCAS2 Regulates Delta-Notch Signaling Activity through Delta Pre-mRNA Splicing in Drosophila Wing Development.

BCAS2 Regulates Delta-Notch Signaling Activity through Delta Pre-mRNA Splicing in Drosophila Wing Development.

Previously, we showed that BCAS2 is essential for Drosophila viability and functions in pre-mRNA splicing. In this study, we provide strong evidence that BCAS2 regulates the activity of Delta-Notch signaling via Delta pre-mRNA splicing. Depletion of dBCAS2 reduces Delta mRNA expression and leads to...

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Bibliographic Details
Main Authors: Meng-Hsuan Chou, Yi-Chen Hsieh, Chu-Wei Huang, Po-Han Chen, Shih-Peng Chan, Yeou-Ping Tsao, Hsiu-Hsiang Lee, June-Tai Wu, Show-Li Chen
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4475048?pdf=render

Internet

http://europepmc.org/articles/PMC4475048?pdf=render

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