From blood to lung tissue: effect of cigarette smoke on DNA methylation and lung function

From blood to lung tissue: effect of cigarette smoke on DNA methylation and lung function

Abstract Background Genetic and environmental factors play a role in the development of COPD. The epigenome, and more specifically DNA methylation, is recognized as important link between these factors. We postulate that DNA methylation is one of the routes by which cigarette smoke influences the de...

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Bibliographic Details
Main Authors: Maaike de Vries, Diana A van der Plaat, Ivana Nedeljkovic, Rikst Nynke Verkaik-Schakel, Wierd Kooistra, Najaf Amin, Cornelia M van Duijn, Corry-Anke Brandsma, Cleo C van Diemen, Judith M Vonk, H Marike Boezen
Format: Article
Language:English
Published: BMC 2018-11-01
Series:Respiratory Research
Subjects:
Cigarette smoking
Lung function
DNA methylation
EWAS
Lung tissue
Online Access:http://link.springer.com/article/10.1186/s12931-018-0904-y

Internet

http://link.springer.com/article/10.1186/s12931-018-0904-y

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