Toll-like receptor-4 coordinates the innate immune response of the kidney to renal ischemia/reperfusion injury.

Toll-like receptor-4 coordinates the innate immune response of the kidney to renal ischemia/reperfusion injury.

Toll-like receptors (TLRs) can detect endogenous danger molecules released upon tissue injury resulting in the induction of a proinflammatory response. One of the TLR family members, TLR4, is constitutively expressed at RNA level on renal epithelium and this expression is enhanced upon renal ischemi...

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Bibliographic Details
Main Authors: Wilco P Pulskens, Gwendoline J Teske, Loes M Butter, Joris J Roelofs, Tom van der Poll, Sandrine Florquin, Jaklien C Leemans
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2008-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2570789?pdf=render

Internet

http://europepmc.org/articles/PMC2570789?pdf=render

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