<i>Streptococcus pneumoniae </i>and its Virulence Factors H<sub>2</sub>O<sub>2</sub> and Pneumolysin are Potent Mediators of the Acute Chest Syndrome in Sickle Cell Disease

<i>Streptococcus pneumoniae </i>and its Virulence Factors H<sub>2</sub>O<sub>2</sub> and Pneumolysin are Potent Mediators of the Acute Chest Syndrome in Sickle Cell Disease

Sickle cell disease (SCD) is one of the most common autosomal recessive disorders in the world. Due to functional asplenia, a dysfunctional antibody response, antibiotic drug resistance and poor response to immunization, SCD patients have impaired immunity. A leading cause of hospitalization and dea...

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Bibliographic Details
Main Authors: Joyce Gonzales, Trinad Chakraborty, Maritza Romero, Mobarak Abu Mraheil, Abdullah Kutlar, Betty Pace, Rudolf Lucas
Format: Article
Language:English
Published: MDPI AG 2021-02-01
Series:Toxins
Subjects:
sickle cell disease
acute chest syndrome
<i>Streptococcus pneumoniae</i>
pneumolysin
H<sub>2</sub>O<sub>2</sub>
Online Access:https://www.mdpi.com/2072-6651/13/2/157

Internet

https://www.mdpi.com/2072-6651/13/2/157

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