Copper induces mitochondria-mediated apoptosis via AMPK-mTOR pathway in hypothalamus of Pigs

Copper induces mitochondria-mediated apoptosis via AMPK-mTOR pathway in hypothalamus of Pigs

Copper (Cu), one of the heavy metals, is far beyond the carrying capacity of the environment with Cu mining, industrial wastewater discharging and the use of Cu-containing pesticides. Intaking excess Cu can cause toxic effects on liver, kidney, heart, but few studies report Cu toxicity on brain tiss...

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Bibliographic Details
Main Authors: Chaiqin Lei, Jianzhao Liao, Quanwei Li, Jian Shi, Hui Zhang, Jianying Guo, Qingyue Han, Lianmei Hu, Ying Li, Jiaqiang Pan, Zhaoxin Tang
Format: Article
Language:English
Published: Elsevier 2021-09-01
Series:Ecotoxicology and Environmental Safety
Subjects:
Copper
Mitochondrion
Apoptosis
AMPK-mTOR pathway
Hypothalamus
Online Access:http://www.sciencedirect.com/science/article/pii/S0147651321005078

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http://www.sciencedirect.com/science/article/pii/S0147651321005078

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