Dissecting the Role of the FGF19-FGFR4 Signaling Pathway in Cancer Development and Progression

Fibroblast growth factor (FGF) receptor 4 (FGFR4) belongs to a family of tyrosine kinase receptor. FGFR4 is highly activated in certain types of cancer and its activation is closely associated with its specific ligand, FGF19. Indeed, FGF19-FGFR4 signaling is implicated in many cellular processes inc...

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Bibliographic Details
Main Authors: Yanan Liu, Meng Cao, Yuepiao Cai, Xiaokun Li, Chengguang Zhao, Ri Cui
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-02-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
Online Access:https://www.frontiersin.org/article/10.3389/fcell.2020.00095/full