Pseudomonas aeruginosa rugose small-colony variants evade host clearance, are hyper-inflammatory, and persist in multiple host environments.

Pseudomonas aeruginosa rugose small-colony variants evade host clearance, are hyper-inflammatory, and persist in multiple host environments.

Pseudomonas aeruginosa causes devastating infections in immunocompromised individuals. Once established, P. aeruginosa infections become incredibly difficult to treat due to the development of antibiotic tolerant, aggregated communities known as biofilms. A hyper-biofilm forming clinical variant of...

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Bibliographic Details
Main Authors: Matthew J Pestrak, Sarah B Chaney, Heather C Eggleston, Sheri Dellos-Nolan, Sriteja Dixit, Shomita S Mathew-Steiner, Sashwati Roy, Matthew R Parsek, Chandan K Sen, Daniel J Wozniak
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-02-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC5812653?pdf=render

Internet

http://europepmc.org/articles/PMC5812653?pdf=render

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