Depletion of CD25+ cells during acute toxoplasmosis does not significantly increase mortality in Swiss OF1 mice

The interleukin (IL)-2R alpha chain (CD25) is expressed on regulatory T cells (Treg), which constitute more than 85% of the CD25+ T cell population in a naïve mouse. CD25 is also expressed on effector T cells in mice suffering from an acute infection by the obligate intracellular protozoan parasite,...

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Bibliographic Details
Main Authors: Haroon Akbar, Stéphanie Germon, Patricia Berthon, Isabelle Dimier-Poisson, Nathalie Moiré
Format: Article
Language:English
Published: Instituto Oswaldo Cruz, Ministério da Saúde 2012-03-01
Series:Memórias do Instituto Oswaldo Cruz.
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762012000200002&lng=en&tlng=en