Coherent functional modules improve transcription factor target identification, cooperativity prediction, and disease association.

Transcription factors (TFs) are fundamental controllers of cellular regulation that function in a complex and combinatorial manner. Accurate identification of a transcription factor's targets is essential to understanding the role that factors play in disease biology. However, due to a high fal...

Full description

Bibliographic Details
Main Authors: Konrad J Karczewski, Michael Snyder, Russ B Altman, Nicholas P Tatonetti
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-02-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC3916285?pdf=render