Coherent functional modules improve transcription factor target identification, cooperativity prediction, and disease association.
Transcription factors (TFs) are fundamental controllers of cellular regulation that function in a complex and combinatorial manner. Accurate identification of a transcription factor's targets is essential to understanding the role that factors play in disease biology. However, due to a high fal...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2014-02-01
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Series: | PLoS Genetics |
Online Access: | http://europepmc.org/articles/PMC3916285?pdf=render |