The α2,3-sialyltransferase encoded by myxoma virus is a virulence factor that contributes to immunosuppression.

Myxoma virus (MYXV) induces a lethal disease called Myxomatosis in European rabbits. MYXV is one of the rare viruses that encodes an α2,3-sialyltransferase through its M138L gene. In this study, we showed that although the absence of the enzyme was not associated with any in vitro deficit, the M138L...

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Bibliographic Details
Main Authors: Bérengère Boutard, Sophie Vankerckhove, Nicolas Markine-Goriaynoff, Mickaël Sarlet, Daniel Desmecht, Grant McFadden, Alain Vanderplasschen, Laurent Gillet
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4338283?pdf=render