Increased gut permeability and bacterial translocation after chronic chlorpyrifos exposure in rats.

The epithelium's barrier function is crucial for maintaining homeostasis and preventing the passage of food antigens and luminal bacteria. This function is essentially subserved by tight junctions (TJs), multiprotein complexes located in the most apical part of the lateral membrane. Some gastro...

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Bibliographic Details
Main Authors: Claire Joly Condette, Hafida Khorsi-Cauet, Patrice Morlière, Luciane Zabijak, Julie Reygner, Véronique Bach, Jérôme Gay-Quéheillard
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4096588?pdf=render