Mayaro Virus Induction of Oxidative Stress is Associated With Liver Pathology in a Non-Lethal Mouse Model

Abstract Mayaro virus (MAYV) causes Mayaro fever in humans, a self-limiting acute disease, with persistent arthralgia and arthritis. Although MAYV has a remerging potential, its pathogenic mechanisms remain unclear. Here, we characterized a model of MAYV infection in 3–4-week BALB/c mice. We investi...

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Bibliographic Details
Main Authors: Camila Carla da Silva Caetano, Fernanda Caetano Camini, Letícia Trindade Almeida, Ariane Coelho Ferraz, Tales Fernando da Silva, Rafaela Lameira Souza Lima, Mayara Medeiros de Freitas Carvalho, Thalles de Freitas Castro, Cláudia Martins Carneiro, Breno de Mello Silva, Silvana de Queiroz Silva, José Carlos de Magalhães, Cintia Lopes de Brito Magalhães
Format: Article
Language:English
Published: Nature Publishing Group 2019-10-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-019-51713-9