Immobilisation of Delta-like 1 ligand for the scalable and controlled manufacture of hematopoietic progenitor cells in a stirred bioreactor

Immobilisation of Delta-like 1 ligand for the scalable and controlled manufacture of hematopoietic progenitor cells in a stirred bioreactor

Abstract Background Umbilical cord blood provides a source of hematopoietic stem cells for transplantation with immunological and availability advantages over conventional bone marrow sources. Limited cell numbers and slower engraftment from umbilical cord blood units has led to the clinical develop...

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Bibliographic Details
Main Authors: Rebecca L. L. Moore, Matthew J. Worrallo, Peter D. Mitchell, Jon Harriman, Katie E. Glen, Robert J. Thomas
Format: Article
Language:English
Published: BMC 2017-08-01
Series:BMC Biotechnology
Subjects:
Cell culture
Ex vivo expansion
Delta-like 1
Hematopoietic progenitor cell
Immobilised
Manufacturing
Online Access:http://link.springer.com/article/10.1186/s12896-017-0383-0

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http://link.springer.com/article/10.1186/s12896-017-0383-0

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