Charting Monosynaptic Connectivity Maps by Two-Color Light-Sheet Fluorescence Microscopy

Cellular resolution three-dimensional (3D) visualization of defined, fluorescently labeled long-range neuronal networks in the uncut adult mouse brain has been elusive. Here, a virus-based strategy is described that allowed fluorescent labeling of centrifugally projecting neuronal populations in th...

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Bibliographic Details
Main Authors: Christian J. Niedworok, Inna Schwarz, Julia Ledderose, Günter Giese, Karl-Klaus Conzelmann, Martin K. Schwarz
Format: Article
Language:English
Published: Elsevier 2012-11-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124712003440