Hyaluronic Acid in the Intestinal Tract: Influence of Structure, Rheology, and Mucoadhesion on the Intestinal Uptake in Rats

Oral hyaluronic acid (HA) is a ubiquitous biopolymer that has gained attention as a treatment for local or systemic diseases. Here, we prepared and characterized structures of free HA (f-HA) with a high (>10<sup>5</sup> Da), intermediate (≤10<sup>5</sup> Da), and low (≤10&...

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Bibliographic Details
Main Authors: Alexandro Barbosa de Souza, Marco Vinícius Chaud, Thais Francine Alves, Juliana Ferreira de Souza, Maria Helena Andrade Santana
Format: Article
Language:English
Published: MDPI AG 2020-10-01
Series:Biomolecules
Subjects:
Online Access:https://www.mdpi.com/2218-273X/10/10/1422