Drug-induced amino acid deprivation as strategy for cancer therapy

Abstract Cancer is caused by uncontrollable growth of neoplastic cells, leading to invasion of adjacent and distant tissues resulting in death. Cancer cells have specific nutrient(s) auxotrophy and have a much higher nutrient demand compared to normal tissues. Therefore, different metabolic inhibito...

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Bibliographic Details
Main Authors: Marcus Kwong Lam Fung, Godfrey Chi-Fung Chan
Format: Article
Language:English
Published: BMC 2017-07-01
Series:Journal of Hematology & Oncology
Subjects:
Online Access:http://link.springer.com/article/10.1186/s13045-017-0509-9