Methodological aspects of MRI of transplanted superparamagnetic iron oxide-labeled mesenchymal stem cells in live rat brain.

In vivo tracking of transplanted mesenchymal stem cells (MSCs) migration and homing is vital for understanding the mechanisms of beneficial effects of MSCs transplantation in animal models of diseases and in clinical trials. Transplanted cells can be labeled with superparamagnetic iron oxide (SPIO)...

Full description

Bibliographic Details
Main Authors: Daria Namestnikova, Ilya Gubskiy, Irina Kholodenko, Pavel Melnikov, Kirill Sukhinich, Anna Gabashvili, Daniil Vishnevskiy, Anastasia Soloveva, Maxim Abakumov, Igor Vakhrushev, Alexei Lupatov, Vladimir Chekhonin, Leonid Gubsky, Konstantin Yarygin
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5648235?pdf=render