The subthalamic microlesion story in Parkinson's disease: electrode insertion-related motor improvement with relative cortico-subcortical hypoactivation in fMRI.

Electrode implantation into the subthalamic nucleus for deep brain stimulation in Parkinson's disease (PD) is associated with a temporary motor improvement occurring prior to neurostimulation. We studied this phenomenon by functional magnetic resonance imaging (fMRI) when considering the Unifie...

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Bibliographic Details
Main Authors: Robert Jech, Karsten Mueller, Dušan Urgošík, Tomáš Sieger, Štefan Holiga, Filip Růžička, Petr Dušek, Petra Havránková, Josef Vymazal, Evžen Růžička
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3492182?pdf=render