Chemovirotherapy of Lung Squamous Cell Carcinoma by Combining Oncolytic Adenovirus With Gemcitabine

Chemovirotherapy of Lung Squamous Cell Carcinoma by Combining Oncolytic Adenovirus With Gemcitabine

Oncolytic virotherapy is emerging as an important agent in cancer treatment. In a previous study, we designed and constructed Ad-Apoptin-hTERTp-E1a (Ad-VT), a dual cancer-selective anti-tumor recombinant adenovirus. In this study, crystal violet staining and WST-1 assays showed that Ad-VT has a sign...

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Bibliographic Details
Main Authors: Xing Liu, Zhiguang Yang, Yiquan Li, Yilong Zhu, Wenjie Li, Shanzhi Li, Jing Wang, Yingli Cui, Chao Shang, Zirui Liu, Gaojie Song, Ce Li, Xiao Li, Guoguang Shao, Ningyi Jin
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-02-01
Series:Frontiers in Oncology
Subjects:
Apoptin
hTERT
recombinant adenovirus
gemcitabine
lung squamous cell carcinoma
Online Access:https://www.frontiersin.org/article/10.3389/fonc.2020.00229/full

Internet

https://www.frontiersin.org/article/10.3389/fonc.2020.00229/full

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