Identification of Dipeptidyl Peptidase-4 and α-Amylase Inhibitors from <i>Melicope glabra</i> (Blume) T. G. Hartley (Rutaceae) Using Liquid Chromatography Tandem Mass Spectrometry, In Vitro and In Silico Methods

Identification of Dipeptidyl Peptidase-4 and α-Amylase Inhibitors from <i>Melicope glabra</i> (Blume) T. G. Hartley (Rutaceae) Using Liquid Chromatography Tandem Mass Spectrometry, In Vitro and In Silico Methods

The present study investigated the antidiabetic properties of the extracts and fractions from leaves and stem bark of <i>M. glabra</i> based on dipeptidyl peptidase-4 (DPP-4) and α-amylase inhibitory activity assays. The chloroform extract of the leaves was found to be most active toward...

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Bibliographic Details
Main Authors: Alexandra Quek, Nur Kartinee Kassim, Amin Ismail, Muhammad Alif Mohammad Latif, Khozirah Shaari, Dai Chuan Tan, Pei Cee Lim
Format: Article
Language:English
Published: MDPI AG 2021-12-01
Series:Molecules
Subjects:
<i>Melicope glabra</i>
antidiabetic
diabetes
DPP-4
α-Amylase
molecular docking
Online Access:https://www.mdpi.com/1420-3049/26/1/1

Internet

https://www.mdpi.com/1420-3049/26/1/1

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