Major role of iron uptake systems in the intrinsic extra-intestinal virulence of the genus Escherichia revealed by a genome-wide association study.

The genus Escherichia is composed of several species and cryptic clades, including E. coli, which behaves as a vertebrate gut commensal, but also as an opportunistic pathogen involved in both diarrheic and extra-intestinal diseases. To characterize the genetic determinants of extra-intestinal virule...

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Bibliographic Details
Main Authors: Marco Galardini, Olivier Clermont, Alexandra Baron, Bede Busby, Sara Dion, Sören Schubert, Pedro Beltrao, Erick Denamur
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-10-01
Series:PLoS Genetics
Online Access:https://doi.org/10.1371/journal.pgen.1009065