MicroRNA-486-3p regulates γ-globin expression in human erythroid cells by directly modulating BCL11A.

MicroRNAs (miRNAs) play key roles in modulating a variety of cellular processes through repression of mRNAs target. The functional relevance of microRNAs has been proven in normal and malignant hematopoiesis. While analyzing miRNAs expression profile in unilineage serum-free liquid suspension unilin...

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Bibliographic Details
Main Authors: Valentina Lulli, Paolo Romania, Ornella Morsilli, Paolo Cianciulli, Marco Gabbianelli, Ugo Testa, Alessandro Giuliani, Giovanna Marziali
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3617093?pdf=render