Effects of nutritional supplementation on fatigue, and autonomic and immune dysfunction in patients with end-stage renal disease: a randomized, double-blind, placebo-controlled, multicenter trial.

Fatigue is a predictor of cardiovascular events in patients with end-stage renal disease (ESRD) undergoing hemodialysis treatment. We hypothesized that multinutritional support would improve quality of life, fatigue symptoms, and potential quantitative measures including endocrine, immune and autono...

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Bibliographic Details
Main Authors: Sanae Fukuda, Hidenori Koyama, Kazuhiro Kondo, Hisako Fujii, Yoshinobu Hirayama, Tsutomu Tabata, Mikio Okamura, Tomoyuki Yamakawa, Shigeki Okada, Sumio Hirata, Hiroshi Kiyama, Osami Kajimoto, Yasuyoshi Watanabe, Masaaki Inaba, Yoshiki Nishizawa
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4352065?pdf=render