Cholesterol Balance in Prion Diseases and Alzheimer’s Disease

Prion diseases are transmissible and fatal neurodegenerative disorders of humans and animals. They are characterized by the accumulation of PrPSc, an aberrantly folded isoform of the cellular prion protein PrPC, in the brains of affected individuals. PrPC is a cell surface glycoprotein attached to t...

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Bibliographic Details
Main Authors: Samia Hannaoui, Su Yeon Shim, Yo Ching Cheng, Erica Corda, Sabine Gilch
Format: Article
Language:English
Published: MDPI AG 2014-11-01
Series:Viruses
Subjects:
Online Access:http://www.mdpi.com/1999-4915/6/11/4505