Phrenic-specific transcriptional programs shape respiratory motor output

Phrenic-specific transcriptional programs shape respiratory motor output

The precise pattern of motor neuron (MN) activation is essential for the execution of motor actions; however, the molecular mechanisms that give rise to specific patterns of MN activity are largely unknown. Phrenic MNs integrate multiple inputs to mediate inspiratory activity during breathing and ar...

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Bibliographic Details
Main Authors: Alicia N Vagnozzi, Kiran Garg, Carola Dewitz, Matthew T Moore, Jared M Cregg, Lucie Jeannotte, Niccolò Zampieri, Lynn T Landmesser, Polyxeni Philippidou
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2020-01-01
Series:eLife
Subjects:
phrenic motor neurons
Hox5 genes
cadherins
respiration
inhibition
PMC (phrenic motor column)
Online Access:https://elifesciences.org/articles/52859

Internet

https://elifesciences.org/articles/52859

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