Transcriptomic analysis of dystrophin RNAi knockdown reveals a central role for dystrophin in muscle differentiation and contractile apparatus organization

<p>Abstract</p> <p>Background</p> <p>Duchenne muscular dystrophy (DMD) is a fatal muscle wasting disorder caused by mutations in the dystrophin gene. DMD has a complex and as yet incompletely defined molecular pathophysiology hindering development of effective ameliorat...

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Bibliographic Details
Main Authors: Graham Ian R, Athanasopoulos Takis, Trollet Capucine, Ghahramani Seno Mohammad M, Hu Pingzhao, Dickson George
Format: Article
Language:English
Published: BMC 2010-06-01
Series:BMC Genomics
Online Access:http://www.biomedcentral.com/1471-2164/11/345