Critical Considerations for the Design of Multi-Organ Microphysiological Systems (MPS)

Identification and approval of new drugs for use in patients requires extensive preclinical studies and clinical trials. Preclinical studies rely on in vitro experiments and animal models of human diseases. The transferability of drug toxicity and efficacy estimates to humans from animal models is b...

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Bibliographic Details
Main Authors: Mridu Malik, Yang Yang, Parinaz Fathi, Gretchen J. Mahler, Mandy B. Esch
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-09-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
MPS
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2021.721338/full