Conjunctival inflammation in thrombospondin-1 deficient mouse model of Sjögren's syndrome.

Lacrimal gland inflammation during autoimmune Sjögren's syndrome (SS) leads to ocular surface inflammation - Keratoconjunctivitis sicca (KCS). This condition afflicts both the cornea and conjunctiva that form the ocular surface. Thrombospondin-1 (TSP-1) deficiency in mice results in lacrimal gl...

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Bibliographic Details
Main Authors: Laura Contreras-Ruiz, Birgit Regenfuss, Fayaz Ahmad Mir, James Kearns, Sharmila Masli
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3781083?pdf=render