T-cell epitope prediction: rescaling can mask biological variation between MHC molecules.

T-cell epitope prediction: rescaling can mask biological variation between MHC molecules.

Theoretical methods for predicting CD8+ T-cell epitopes are an important tool in vaccine design and for enhancing our understanding of the cellular immune system. The most popular methods currently available produce binding affinity predictions across a range of MHC molecules. In comparing results b...

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Bibliographic Details
Main Authors: Aidan MacNamara, Ulrich Kadolsky, Charles R M Bangham, Becca Asquith
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-03-01
Series:PLoS Computational Biology
Online Access:http://europepmc.org/articles/PMC2650421?pdf=render

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http://europepmc.org/articles/PMC2650421?pdf=render

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