A sexually dimorphic pre-stressed translational signature in CA3 pyramidal neurons of BDNF Val66Met mice

Animals’ response to acute stress is known to be influenced by sex and genetics. Here the authors performed RNA-seq on actively translated mRNAs in hippocampal CA3 neurons in mice, and document the effects of sex and genotype (i.e., BDNF Val66Met) on acute stress-induced gene expression.

Bibliographic Details
Main Authors: Jordan Marrocco, Gordon H. Petty, Mariel B. Ríos, Jason D. Gray, Joshua F. Kogan, Elizabeth M. Waters, Eric F. Schmidt, Francis S. Lee, Bruce S. McEwen
Format: Article
Language:English
Published: Nature Publishing Group 2017-10-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-017-01014-4