Non-Pathogenic Mopeia Virus Induces More Robust Activation of Plasmacytoid Dendritic Cells than Lassa Virus

Non-Pathogenic Mopeia Virus Induces More Robust Activation of Plasmacytoid Dendritic Cells than Lassa Virus

Lassa virus (LASV) causes a viral haemorrhagic fever in humans and is a major public health concern in West Africa. An efficient immune response to LASV appears to rely on type I interferon (IFN-I) production and T-cell activation. We evaluated the response of plasmacytoid dendritic cells (pDC) to L...

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Bibliographic Details
Main Authors: Justine Schaeffer, Stéphanie Reynard, Xavier Carnec, Natalia Pietrosemoli, Marie-Agnès Dillies, Sylvain Baize
Format: Article
Language:English
Published: MDPI AG 2019-03-01
Series:Viruses
Subjects:
Lassa virus
Mopeia virus
viral haemorrhagic fever
plasmacytoid dendritic cells
type I interferon
Online Access:https://www.mdpi.com/1999-4915/11/3/287

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https://www.mdpi.com/1999-4915/11/3/287

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