Detection of In Vivo Inflammasome Activation for Predicting Sepsis Mortality

Detection of In Vivo Inflammasome Activation for Predicting Sepsis Mortality

Sepsis is a severe life-threatening syndrome caused by dysregulated host responses to infection. Biomarkers that allow for monitoring the patient’s immune status are needed. Recently, a flow cytometry-based detection of in vivo inflammasome activation by formation of cytoplasmic aggregates of ASC (a...

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Bibliographic Details
Main Authors: Jing Cui, Stephanie Oehrl, Fareed Ahmad, Thorsten Brenner, Florian Uhle, Christian Nusshag, Christoph Rupp, Felix Funck, Stefan Meisel, Markus A. Weigand, Christian Morath, Knut Schäkel
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-02-01
Series:Frontiers in Immunology
Subjects:
inflammasome
sepsis
monocytes
biomarker
ASC-speck
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2020.613745/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2020.613745/full

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