Targeting imperfect vaccines against drug-resistance determinants: a strategy for countering the rise of drug resistance.

The growing prevalence of antimicrobial resistance in major pathogens is outpacing discovery of new antimicrobial classes. Vaccines mitigate the effect of antimicrobial resistance by reducing the need for treatment, but vaccines for many drug-resistant pathogens remain undiscovered or have limited e...

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Bibliographic Details
Main Authors: Regina Joice, Marc Lipsitch
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3723804?pdf=render