In Vitro Sensitivity to Venetoclax and Microenvironment Protection in Hairy Cell Leukemia

In Vitro Sensitivity to Venetoclax and Microenvironment Protection in Hairy Cell Leukemia

Current standard treatment of patients with hairy cell leukemia (HCL), a chronic B-cell neoplasia of low incidence that affects the elderly, is based on the administration of purine analogs such as cladribine. This chemotherapy approach shows satisfactory responses, but the disease relapses, often r...

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Bibliographic Details
Main Authors: Alexia Vereertbrugghen, Ana Colado, Ernesto Gargiulo, Raimundo Fernando Bezares, Horacio Fernández Grecco, Gregorio Cordini, Maria del Rosario Custidiano, Jean-Hugues François, Guy Berchem, Mercedes Borge, Jerome Paggetti, Etienne Moussay, Romina Gamberale, Mirta Giordano, Pablo Elías Morande
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-07-01
Series:Frontiers in Oncology
Subjects:
hairy cell leukemia
ABT-199
cell death
leukemia microenvironment
venetoclax
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2021.598319/full

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https://www.frontiersin.org/articles/10.3389/fonc.2021.598319/full

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