The prognostic significance of IRF8 transcripts in adult patients with acute myeloid leukemia.

The prognostic significance of IRF8 transcripts in adult patients with acute myeloid leukemia.

Interferon regulatory factor 8 (IRF8) is a transcription factor that plays a critical role in normal hematopoiesis, such that disruption of IRF8 activity promotes leukemogenesis. We and others have identified aberrant expression of IRF8 transcripts, including novel splice variants, in acute myeloid...

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Main Authors: Era L Pogosova-Agadjanyan, Kenneth J Kopecky, Fabiana Ostronoff, Frederick R Appelbaum, John Godwin, Hana Lee, Alan F List, Jennifer J May, Vivian G Oehler, Steve Petersdorf, Galina L Pogosov, Jerald P Radich, Cheryl L Willman, Soheil Meshinchi, Derek L Stirewalt
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3743845?pdf=render

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http://europepmc.org/articles/PMC3743845?pdf=render

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