Acacetin Blocks Kv1.3 Channels and Inhibits Human T Cell Activation

Backgrounds/Aims: Acacetin, a natural flavonoid compound, has been proven to exert anti-inflammatory and immunomodulatory effects. Kv1.3 channels, highly expressed in human T cells, are attractive therapeutic targets to treat inflammatory and immunological disorders. The present study was designed t...

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Bibliographic Details
Main Authors: Ning Zhao, Qian Dong, Xiao-Xing Fu, Li-Li Du, Xiang Cheng, Yi-Mei Du, Yu-Hua Liao
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2014-10-01
Series:Cellular Physiology and Biochemistry
Subjects:
Online Access:http://www.karger.com/Article/FullText/366343