An integrative genomic and epigenomic approach for the study of transcriptional regulation.

An integrative genomic and epigenomic approach for the study of transcriptional regulation.

The molecular heterogeneity of acute leukemias and other tumors constitutes a major obstacle towards understanding disease pathogenesis and developing new targeted-therapies. Aberrant gene regulation is a hallmark of cancer and plays a central role in determining tumor phenotype. We predicted that i...

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Bibliographic Details
Main Authors: Maria E Figueroa, Mark Reimers, Reid F Thompson, Kenny Ye, Yushan Li, Rebecca R Selzer, Jakob Fridriksson, Elisabeth Paietta, Peter Wiernik, Roland D Green, John M Greally, Ari Melnick
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2008-03-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2266992?pdf=render

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http://europepmc.org/articles/PMC2266992?pdf=render

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