An integrative genomic and epigenomic approach for the study of transcriptional regulation.
The molecular heterogeneity of acute leukemias and other tumors constitutes a major obstacle towards understanding disease pathogenesis and developing new targeted-therapies. Aberrant gene regulation is a hallmark of cancer and plays a central role in determining tumor phenotype. We predicted that i...
Main Authors: | Maria E Figueroa, Mark Reimers, Reid F Thompson, Kenny Ye, Yushan Li, Rebecca R Selzer, Jakob Fridriksson, Elisabeth Paietta, Peter Wiernik, Roland D Green, John M Greally, Ari Melnick |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2008-03-01
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Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC2266992?pdf=render |
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