NLRP3 Inflammasome Modulation by Melatonin Supplementation in Chronic Pristane-Induced Lupus Nephritis

NLRP3 Inflammasome Modulation by Melatonin Supplementation in Chronic Pristane-Induced Lupus Nephritis

Lupus nephritis (LN) is a kidney inflammatory disease caused by systemic lupus erythematosus (SLE). NLRP3 inflammasome activation is implicated in LN pathogenesis, suggesting its potential targets for LN treatment. Melatonin, an endogenous indoleamine, is considered an important multitasking molecul...

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Bibliographic Details
Main Authors: Francesca Bonomini, Mariane Dos Santos, Francisco Veríssimo Veronese, Rita Rezzani
Format: Article
Language:English
Published: MDPI AG 2019-07-01
Series:International Journal of Molecular Sciences
Subjects:
Lupus nephritis
oxidative stress
inflammation
melatonin
Online Access:https://www.mdpi.com/1422-0067/20/14/3466

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https://www.mdpi.com/1422-0067/20/14/3466

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